L-CARNOSINE
Anti-Aging and Antioxidant Neuropeptide
See also: L-Carnosine Abstracts
 L-CARNOSINE contains 500 mg of pharmaceutical-grade l-carnosine in a preservative-free gelatin capsule.
NUTRITIONAL CONSIDERATIONS & APPLICATIONS:
The dipeptide l-carnosine is a well-known neuropeptide consisting of alanine and histidine (beta-alanyl-l-histidine). It is normally made in the human body and found at high levels in brain, innervated tissues, the eye lens, and skeletal muscle tissue.
Laboratory studies have demonstrated l-carnosine's ability to protect cells against oxidative stress and to increase cells' resistance to functional exhaustion and the accumulation of senile features. The mechanisms of this protection are explicable in terms of proton buffering (maintaining pH balance), heavy metal chelation (of especially copper and zinc), free-radical and active sugar molecule scavenging (which counters the glycation of proteins), and preventing modification of biomacromolecules (thereby preserving their native functionality under oxidative stress).
Physiological concentrations (20-30 mM) in standard media prolong the in vitro lifespan of human fibroblast cells and reduce strongly the normal features of senescence (aging). L-carnosine clearly has improved the external appearance of experimental animals, and produced beneficial effects both on behavioral parameters and average life span.
L-carnosine may be effective for age-related conditions, including: 1) Neurological degeneration, 2) Cellular senescence, 3) Cross-linking of skin collagen and/or the eye lens, 4) Accumulation of damaged proteins, 5) Muscle atrophy, 6) Brain circulation deficit, 7) LDL cholesterol oxidation, 8) DNA chromosome damage, and 9) Formation of Advanced Glycation End Products (AGEs). L-carnosine is non-toxic and normally is obtained from meats in the diet.
COMPOSITION: 1 preservative-free capsule provides the following percentage of the Daily Value:
| NUTRIENT |
AMOUNT |
% Daily Value |
L-Carnosine |
500 mg |
No established Daily Value |
DIRECTIONS: As a dietary supplement take 1 capsule daily away from food, or as directed by a health care professional.
INGREDIENTS: L-Carnosine only contains pharmaceutical grade (greater than 99% pure) l-carnosine, gelatin (capsule), magnesium trisilicate, and magnesium stearate.
L-Carnosine does not contain wheat, rye, oats, corn, barley, gluten, soy, egg, dairy, yeast, sugar, wax, preservatives, colorings, or artificial flavorings.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
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