Welcome to HPDI!

Full Product Overview

PDF Download

 The pdf download is being rewritten to include the latest information


Foundational Supplements Pie DiagramFoundational Supplements

We consider Foundational Supplements to include multivitamins, essential fatty acid formulas, antioxidant vitamin C products, Rejuvenate!™ superfoods (providing high levels of nucleic acids), gut health formulas, and hydrogen products.

When all six types of foundational supplements are included in your program of nutrition, you can expect health results far beyond your gains from a subset of these formulas. This is because Foundational Supplements cooperate synergistically in support of optimal health. Foundational Supplements comprise a complete system of essential nutritional supplementation that can provide benefits greatly exceeding those attainable soley through diet or when taking just a multivitamin on its own.



Multivitamins Icon

Critical nutrients provided by multivitamins include a spectrum of essential vitamins, minerals, and cofactors. These include trace minerals, fat-soluble vitamins (A, E, D, and K), coenzyme B vitamins, magnesium, and other nutrients often missing in modern diets.

  1. Kids Chewable Mighty-Multi: Full-spectrum essential nutrients needed for building, supporting, and maintaining excellent health for your child. Includes coenzyme form vitamins and Krebs cycle bionutrients that work with young bodies to provide needed energy levels. Delicious taste!
  2. Mighty Multi-Vite!™: Recent nutritional research is incorporated into our top-of-the-line “Hank & Brian’s™” multivitamin formula containing the highest-quality and most readily usable forms of vitamins and minerals. The formula includes methylcobalamin, 5-MTHF, and Vitamin K2.
  3. Mini Multi: “Ultrapure” multivitamin and multimineral supplement containing no fillers, additives, or other excipients. Veggie capsule make Mini Multi ideal for vegans. Formulated especially for hypersensitive and/or chemically sensitive individuals, or individuals looking for an additive-free multivitamin.
  4. Multi Two: Our most popular HPDI-brand multivitamin. The highest-purity therapeutic multiple vitamin with minerals and cofactors—does not contain iron. The formula includes methylcobalamin, 5-MTHF, and Vitamin K2. Avalable in capsules and tablets. This formula provides higher levels of B vitamins than Mighty Multi-Vite!.


Vitamin C / Antioxidants

Vitamin C / Antioxidants

Combined with other antioxidants and polyphenols, Vitamin C is crucial for robust health. These groups of nutrients are immune builders, antimicrobials, detoxifiers, connective tissue builders, and they stimulate key endogenous enzymes via Nrf2.

  1. Vitamin C 1,000 Capsules: Vitamin C as ascorbic acid in convenient one (1) gram capsules.
  2. Buffered Vitamin C Powder: Buffered with calcium, magnesium, potassium, and zinc.
  3. Buffered C 1,000 Tablets: Vitamin C source from calcium and magnesium ascorbate in one (1) gram tablets.
  4. Liposomal Vitamin C with R-Lipoic AcidThe most absorbable form of professional-grade VitaminC. Combined with R-Lipoate in a nanoliposomal delivery system, the product potently harnesses the potential of Vitamin C to the power of a fully functioning glutathione system.
  5. Liposomal Glutathione: The Phospholipid Encapsulation Etheric Delivery system protects the glutathione from digestive enzymes that otherwise inhibit absorption of oral glutathione supplementation. Brings the power of intravenous therapy into a convenient oral delivery.
  6. OPC-C™: Super-antioxidant formula with BioVin® grape extract (pulp, skin, and seed) and Vitamin C fully buffered with calcium, magnesium, and zinc.
  7. PRO-C™: Buffered non-GMO Vitamin C with BioVin® grape extract (pulp, skin, and seed), green tea extract (>95% polyphenols), reduced glutathione, NAC, r-lipoic acid, selenium, and immune supporting nutrients. Unique formulation and effective synergistic action make PRO-C™ a “top-of-the-line” formula!
  8. Ultimate Protector™: A next-generation cell protection formula that simultaneously meets the needs for high levels of non-GMO Vitamin C, full spectrum antioxidants (high ORAC value), and protective enzyme activators (Nrf2 activators) in a single product. The formula provides an ORAC5.0™ value of 486,000 units per serving!


Essential Fats

Essential Fats

Essential fatty acids are necessary for vibrant health. They support healthy joints, blood vessels, immunity, oxygen transport to tissues, kidney function, and other biological processes.

  1. Essential Fats plus E: Uniquely balanced omega-3 and omega-6 fatty acids with mixed tocotrienols and tocopherols from rice bran. Includes EPA and DHA from fish oils, and GLA from borage seeds. This complete EFA formula is another “Hank & Brian's” exclusive product.


High RNA Superfoods


Dietary nucleic acids are essential nutrients required for health as proven by Dr. Benjamin Frank. We developed our Rejuvenate!™ superfoods to provide dietary nucleic acids (RNA/DNA) in sufficient quantities to support optimal health.

  1. Chlorella: We have discontinued chlorella. As a superior substitute, we recommend Rejuvenate! Original, the most chlorella-rich of our high-RNA Rejuvenate!™ superfoods.
  2. Rejuvenate!™ Original: A unique, synergistic, high-RNA formula containing chlorella, spirulina, d-ribose, nutritional yeast, chia seeds, rice bran solubles, Vitamin C, chlorella growth factor (CGF), magnesium, dulse, kelp, yeast RNA, folinic acid, and methylcobalamin (B12). The formula provides nutrients supporting detoxification, optimal regeneration, repair, growth, and healing processes in your body.
  3. Rejuvenate!™ Berries & Herbs: A delicious, high-RNA and high-protein superfood that includes organic freeze-dried blueberries, cranberries, raspberries, and strawberries. It also contains a complete cell-protective blend of organic and wildcrafted herbs and antioxidants. Rejuvenate!™ Berries & Herbs is a nutritionally complete formula that contains significant amounts of RNA/DNA, protein, essential fats, fiber, a coenzyme multivitamin, and enzymes. It is the tastiest superfood we have developed, and it mixes well in smoothies, fruit juices, fruit salads, cereal dishes, and plain water.
  4. Rejuvenate!™ PLUS: A complete, high-RNA, high-protein, sweet green superfood. It is uniquely designed to provide all the nutrients you need to thrive, including high-quality protein, essential fats, vitamins (including a coenzyme form B complex), minerals, great-tasting green foods, and high-potency nucleic acids (RNA/DNA), nucleotides, nucleosides, and nucleic acid precursors (e.g., d-ribose) that build powerful health.
  5. Beef Liver capsules: Sourced exclusively from grass-fed, pasture-raised, New Zealand bovine, Beef Liver is an abundant source of nutrients, including protein, RNA and DNA, vitamin B6 and B12, folate, choline, copper, hyaluronic acid, CoQ10, and is one of the most concentrated sources of preformed vitamin A (retinol).


Gut Health

Gut HealthRecent research demonstrates the importance of the microbiome to human health and the damage the microbiome experiences from toxic chemicals in our food and medical systems. It is now known that these toxic chemicals both destroy gut bacteria and cause the tight junctions in our intestines to open up and become leaky.

  1. Restore for Gut Health (8 oz): RESTORE gut health formula rebuilds the microbiome and stops leaky gut by closing the tight junctions.
  2. Restore for Gut Health (32 oz)
  3. TerraFlora™ Synbiotic: Terraflora™ is a unique and effective broad-spectrum synbiotic formulated with a combination of soil-based spore-form probiotics and ancient organic food-based prebiotics designed for robust support of gastrointestinal health.


HydrogenHydrogen is the first and most abundant element in the Universe! Negative hydrogen ions (H-) and molecular hydrogen gas, H2, are the smallest and most mobile substances. This exclusive property gives them greater cellular bioavailability than any other nutrient or nutraceutical. They can rapidly diffuse into cells, mitochondria, and fluids throughout the body to deliver their unique and extremely powerful energy producing and antioxidant benefits.

  1. Active H2 Ultra: A unique combination of all-natural minerals generate Molecular Hydrogen and electron-rich potential (-ORP).
  2. MegaHydrate: This unique hydrogen product greatly enhances the production of ATP (cellular energy) in the body, is the most powerful antioxidant available, and is the key that unlocks the potential of water as the medium for nutrient replenishment and waste removal at the cellular level.

Enhancement Formulas

Enhancement Formulas

Enhancements provide total-body nutritional support beyond Foundational Supplements and are part of a complete nutritional supplement program. Enhancements work best when used in conjunction with Foundational Supplements.

  1. Ancient Minerals Magnesium Products: See below under magnesium flakes, gel, lotion, and oil.
  2. B12 Methylcobalamin: 5 mg sublingual tablets with Vitamin B12 as methylcobalamin. This is the coenzyme form of B12 shown to be readily assimilable and needed for many critical functions in the body.
  3. B-Complex-50: The highest-quality B vitamins with coenzyme forms of B1, B2, B6, B12, folate, and pantethine. Coenzyme forms mean rapid assimilation.
  4. Bone Guardian: Nutrition for bones and joints—this is a synergistic calcium and magnesium formula with hydroxyapatite, magnesium diglycinate, boron, chondroitin sulfate, and supporting nutrients.
  5. Bone Jour!™: Your connective tissues, nerves, and muscles depend on a wide range of nutrients in addition to calcium. Includes magnesium, vitamin D, vitamins K1 and K2, and strontium. A “Hank & Brian's” exclusive “top-of-the-line” bone building and connective tissue support formula.
  6. Coenzyme Q10 Plus: Product discontinued. See Ubiquinol-50 as a superior replacement.
  7. C-60100ml of Organic Extra Virgin Olive Oil fully saturated with solvent-free, research grade Carbon 60 (0.8 mg / ml). Carbon 60 Olive Oil is a product for scientific research.
  8. Complete E: Oil extract of rice bran with approximately equal amounts of alpha and gamma tocotrienols and 31 IU of d-alpha tocopherol, as well as all of the other known natural tocotrienols and tocopherols. GMO and soy free!
  9. Crystal Energy: Instantly turns water into a liquid crystal and more closely matches water surrounding the cells in the body. It increases the flow of water across cell membranes 2.54 times faster than ordinary water, increasing hydration of cells and the flow of nutrients into cells and of toxins coming out of cells by up to 96 times.
  10. Cucurmin C3 Complex®: 250 mg of the highest-quality (65:1 extract) of Curcuma longa (turmeric) standardized to 95% min. curcuminoids. The extract contains bisdemethoxycurcumin (2.2 – 6.5%), demethoxycurcumin (15 –19%), and curcumin (75 – 81%). These ingredients are combined with BioPerine® in a veggie capsule.
  11. Digase: Digestive enzyme formula (now in a veggie cap) contains a full spectrum of digestive enzymes, including proteases optimized for pHs of 3.0, 4.5 and 6.0, as well as peptidase, lipase, and carbohydrases (including amylase, glucoamylase, invertase (sucrase), maltase, alpha-galactosidase, lactase, phytase, cellulase, and hemicellulase); also includes the digestion-stimulating herbs ginger root, gentian root, and caraway seed.
  12. Double Zinc Plus: Zinc picolinate and citrate with coenzyme active Vitamin B6 (P5P).
  13. Liquid Folic Acid: Four-ounce bottle of folic acid dissolved in distilled water and buffered and stabilized with potassium ascorbate. One drop contains approximately 100 mcg of folic acid.
  14. Ginkgo Biloba: Standardized to 24/6 percent ginkgo biloba extract—improves blood flow in microvessels and enhances memory.
  15. Glu-Nac Plus™: An immune builder containing 250 mg reduced glutathione, 250 mg n-acetyl-l-cysteine (NAC), 100 mg alpha-lipoic acid and 20 mcg of selenium.
  16. Immune-Assist™ Daily Formula: More than 200 different polysaccharides, derived from the enzymatic breakdown of complex organic plant material from six different species of medicinal mushrooms. These include Agaricus blazei, Cordyceps sinensis hybrid, Lentinula edodes, Grifola frondosa, Ganoderma lucidum, and Coriolus versicolor. Immune-Assist™ Daily Formula contains 500 mg per vegetarian capsule and is made in America using only USDA Certified Organic materials. Human, animal, and in vitro studies confirm that Immune-Assist™ consistently and effectively boosts immune system function.
  17. L-5-MTHF ((6S)-5-methyltetrahydrofolate): An important naturally occurring folate coenzyme—especially important for dealing with high homocysteine levels in the body. L-5-MTHF can meet all of the body's needs for a folate vitamin.
  18. Liposomal Colorado Hemp OilFaster, stronger and more effective, liposomal delivery of Nanoemulsified Colorado Hemp Oil far outpaces tinctures. The advanced technology behind this groundbreaking liquid delivery method makes for precise dosing and immediate effect.
  19. Lugol's Iodine 2%: Helps prevent iodine deficiency and helps with thyroid function.
  20. Magnesium Lotion (Ancient Minerals) : An ultra-pure, highly concentrated form of magnesium chloride (MgCl2). From the ancient Zechstein seabed in Europe, and blended with certified organic vegetable glycerin, jojoba oil, coconut oil, and shea butter.
  21. Magnesium Oil (Ancient Minerals): Ultra-pure and highly concentrated form of magnesium chloride. Ideal for application across the skin for rapid absorption and healing. Fast becoming a preferred mode for boosting magnesium levels. Excellent for muscle tension, cardiovascular health, better sleep, improved energy (boosts ATP), fibryomyalgia, joint health, etc. We recommend this product for everyday use in baths, footbaths, lotions, and directly on skin.
  22. Magnesium Flakes (Ancient Minerals): Ultra-pure, highly concentrated crystals of magnesium chloride (MgCl2) sourced from the ancient Zechstein seabed in Europe. The flakes provide high levels of magnesium (47% magnesium chloride) and trace elements. Magnesium flakes are especially beneficial when used in baths or footbaths. They are a cost-effective means to raise levels magnesium in the body via transdermal application.
  23. Magnesium Gel Plus (Ancient Minerals): Ultra-pure, highly concentrated form of magnesium chloride (MgCl2). Blended with certified organic, biologically active Aloe Vera extract (200:1) that has a minimum of 10% polysaccharides. The gel provides high levels of magnesium (29% magnesium chloride) and trace elements from pure, unpolluted deposits in the ancient Zechstein seabed. It is especially useful for healing skin conditions because it safely can remain on skin for long periods of time.
  24. Megahydrate: The ultimate hydrogen product. it greatly enhances the production of ATP (cellular energy) in the body, is the most powerful antioxidant available, and is the key that unlocks the potential of water as the medium for nutrient replenishment and waste removal at the cellular level.
  25. MSM: Greater than 99.9% pure MSM (methylsulfonylmethane from OPTIPure®). A source of sulfur—a mineral element critical to the normal function and structure of the human body.
  26. MYO-MAG: Magnesium and malic acid formula with coenzyme forms of Vitamin B1, Vitamin B2, and Vitamin B6. Enhances energy levels by supporting energy production (ATP) In the body. Works well with magnesium oil to boost magnesium levels in the body.
  27. N-Acetyl-L-Cysteine (NAC): Important antioxidant, amino acid, and precursor to glutathione; has mucolytic properties.
  28. Nanoemulsified Milk Thistle: Milk thistle, or Silybum marianum, has been utilized worldwide for over 2,000 years for its remarkable ability to protect and support the liver and can aid healthy digestive function.
  29. Nascent Iodine: Highly-bioavailable atomic form of iodine available in one-ounce and four-ounce tincture bottles. Provides benefits for metabolism and thyroid function, boosts energy levels, supports detoxification systems, immune function, infection fighter, and much more.
  30. Olive Leaf Extract: Patented olive leaf extract. A powerful antimicrobial agent and immune enhancer.
  31. pH ADJUST: may be used to increase salivary and urinary pH; counteract overly acidic conditions in the digestive tract, blood, and kidneys; and to supplement the body with the minerals potassium, magnesium, and sodium.
  32. TerraFlora™ Synbiotic: Terraflora™ is a unique and effective broad-spectrum synbiotic formulated with a combination of soil-based spore-form probiotics and ancient organic food-based prebiotics designed for robust support of gastrointestinal health.
  33. Prolyt: Proteolytic enzyme formula with bromelain, the pancreatic enzymes trypsin and chymotrypsin, turmeric extract (95% curcuminoids), quercetin, and BioVin® grape extract (pulp, skin, and seed). Fights inflammation and helps protein digestion and assimilation. Full-spectrum proteolytic enzyme supplement.
  34. Quercetin Plus: a blend of bioflavonoids/polyphenols in a veggie cap. Includes the highest-purity quercetin, rutin, and oligomeric proanthocyanidins (OPC) from grape extract (pulp, skin and seeds). 
  35. Selenium: The highest-quality l-selenomethionine suitable for hypersensitive individuals.
  36. Tri-Mag: Magnesium from diglycinate, Krebs cycle bionutrients and ascorbate—provides energy building blocks and synergistic nutrients.
  37. Ubiquinol-50: A superior coenzyme Q10 product providing 50 mg of the stabilized reduced form of coenzyme Q10 in a softgel capsule. The product includes D-limonene oil (emulsifier), caprylic acid, capric acid, and alpha-lipoic acid.
  38. Vitamin D3 Plus: An advanced Vitamin D formula providing high-dose Vitamin D3, the natural form of Vitamin D produced in the body from sunlight and the best form for therapeutic purposes.


Specific Condition Formulas

Specific Conditions

Specific Condition Formulas support the body’s efforts to resolve specific health issues. These include problems with joints, eyes, and prostate, as well as issues with blood sugar, allergies, cognitive function, sleep, etc.

  1. Adreno-Plus™: Glandular extracts and synergistic nutrients specifically targeted to support adrenal function.
  2. Allergy Support Plus™: Synergistic nutrients supporting the body naturally during allergic reactions. A thoroughly designed formula effective for all allergies.
  3. Blood Sugar Support (formerly Diabetes Support Formula): Synergistic formula for diabetics, containing Gymnema sylvestre standardized extract, Pterocarpus marsupium standardized extract, bitter melon extract, alpha-lipoic acid, BioVin® grape extract (pulp, skin and seed), magnesium, Vitamin B6, Vitamin B1, Vitamin A, zinc, manganese, biotin, vanadium, chromium, copper, and Bioperine® (black-pepper extract). Highly effective formula supporting blood-sugar control and offering nutritional maintenance for glycemic-related conditions.
  4. Eye & Vision Formula: Hank Liers' original formula specifically designed to build, support, maintain, and improve the health of eyes and the visual system. Seeing is believing! Eye & Vision Formula will be particularly effective when used in conjunction with Visual Ocuity Eye Drops with 1% N-Acetyl-L-Carnosine)!
  5. Hepa Plus: Nutritional support for liver function—includes silymarin, dandelion, lipoic acid, Vitamin B1 (coenzyme form), NAC, ornithine, selenium, alpha-ketoglutarate, molybdenum, glycine, and taurine.
  6. I3C Plus: Steroid hormone balancing substances including indole-3-carbinol (I3C), diindolylmethane (DIM), betaine hydrochloride and ascorbic acid.
  7. Intestinal Rejuvenation Formula: A formula designed to support the health of the gastrointestinal tract. Highly effective detoxifying and healing formula for the bowel. Cleanses the entire digestive tract by drawing toxins, clearing blockages, and supporting natural movement.
  8. Joint Health Formula: A synergistic formula for healthy supple joints containing glucosamine, MSM, sea cucumber, boswellia, rutin, turmeric, and grape extract plus synergistic nutrients. A formula uniquely effective for supporting, building, and maintaining the health of joints and connective tissues.
  9. L-5-HTP (L-5-hydroxytryptophan): A precursor of serotonin, a brain chemical involving pain, appetite, sleep, and mood control.
  10. Prosta Plus: Contains saw palmetto and stinging nettle root extracts, pumpkin seed extract, diindolylmethane (DIM), betasitosterol, pygeum (2.5%), flower pollen extract (20:1), NAC, alanine, glycine, and glutamic acid. Highly effective male formula—it just works!
  11. PS-100 Plus™(Phosphatidylserine): A nutraceutical blend of phosphatidylserine, phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, and the fatty acids caprylic acid, capric acid, palmitic acid, oleic acid, linoleic acid, and linolenic acid. Boosts brain power and supports cell membrane health.
  12. Warrior Mist: A revolutionary new and extraordinarily effective topical pain reliever that delivers fast relief directly at the source of the pain.
  13. Warrior Sleep: A revolutionary transdermal formula that brings deep relaxation, a feeling of well-being, and sleep without drowsiness the next day.
  14. Visual Ocuity: A natural and soothing eye drop formula including lubricants, antioxidants, and buffering agents designed to support healthy eye function. Highly effective formula and a customer favorite.


2DOCS Pet Supplements


2DOCS pet supplements are designed around the simple principle that dogs and cats are just as physiologically complex and in need of nutritional supplementation as humans. Human dietary needs aren't exactly the same as your pet, of course, but the underlying nutritional building blocks are. That’s why 2DOCS pet supplements are based upon human-grade formulas and ingredients.

  1. Essential Fats for Pets: A fatty acid formula containing eicosapentanoic acid (EPA) and docosahexaenoic acid (DHA) (usable forms of essential omega-3 fatty acids from fish oil), gamma linolenic acid (GLA) from borage oil (an essential omega-6 fatty acid), and mixed tocotrienols and tocopherols (from rice bran).
  2. Large Pet Mighty-Multi: An advanced daily formula for large pets containing the highest-quality human-grade vitamins, minerals, cofactors, and herbs. Taste enhanced with fish and liver flavoring.
  3. Small Pet Mighty-Multi: An advanced daily formula for small pets containing the highest-quality human-grade vitamins, minerals, cofactors, and herbs. Taste enhanced with fish and liver flavoring.


Ointments / Etc.

  1. d-Lenolate Topical Skin Treatment Formula: provides natural solutions to fight chronic skin problems. Includes patented olive leaf extract and aloe vera, with MSM, vitamins A, C, and E, distilled water, and gotu kola.
  2. FROLOV's RESPIRATION TRAINING DEVICE: A simple, yet effective respiratory trainer utilizing the concept of resistance breathing in a 20 minute exercise regime.
  3. Relief Rx™: an entirely new kind of relief - like nothing you've ever tried before. It goes on silky smooth and gently absorbs into the skin to provide comfort when and where you need it most. Packaged for a busy lifestyle in a convenient on-the-go tube, just one generous dab is what the body needs to relieve muscle and joint stress.
  4. Super Salve: Antioxidant, antibacterial, and antifungal salve for the soothing and healing relief of dry and cracked skin, chapped lips, abrasions, eczema, and insect bites. This formula originated as a remedy for Grand Canyon river runners and hikers.